Supercooled Ex-Vivo Porcine VCA Preservation to Extend the Timeline Between Procurement and Transplantation and Enable Tolerance Induction to Eliminate Immunotherapy Needs and Risks

Abstract

The project aims to develop a novel technology to preserve vascular composite allografts for extended periods. This project uses a porcine model. In the first year, the focus was on scaling up the prior rat limb perfusion modality to porcine scale.

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Document Details

Document Type
Technical Report
Publication Date
Aug 01, 2020
Accession Number
AD1111631

Entities

People

  • Korkut Uygun

Organizations

  • Massachusetts General Hospital

Tags

Communities of Interest

  • Biomedical

DTIC Thesaurus Topics

  • Abstracts
  • Allografts
  • Arteries
  • Biomedical Research
  • Cold Storage
  • Composite Materials
  • Contracts
  • Electronic Mail
  • Health Services
  • Ischemia
  • Medical Personnel
  • Patent Applications
  • Potassium
  • Procurement
  • Recovery
  • Supercooling
  • Terminals

Readers

  • Distributed Systems and Data Platform Development
  • Trauma Surgery or Emergency Medicine.

Technology Areas

  • Biotechnology