Optical Imaging Falloposcope for Early Ovarian Cancer Detection: In Vivo Feasibility and Safety

Abstract

The goal of our project is to demonstrate that advanced imaging of the fallopian tubes and proximal ovary surface can be performed in women via a minimally invasive approach (no tissue cutting, endoscope introduced into the fallopian tube through a conventional hysteroscope),with no clinically relevant tissue damage, and in a reasonable period of time. This year, we have built and certified a portable, operating room-ready falloposcope imaging system. Were placed large light sources with small fiber-coupled laser diodes, created a compact OCT system, rack mounted the hardware, built disposable, simplified but high performance falloposcopes, wrote improved software, and fully tested an operating room-ready, easily manufacturable, falloposcopy system. All University of Arizona and Banner University Medical Center approvals have been obtained. We have tested the system in phantoms and have a journal manuscript on the falloposcope accepted. We are awaiting the reopening of clinical research at Banner, closed due to high volume of COVID-19 patients, to begin in vivo trials.

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Document Details

Document Type
Technical Report
Publication Date
Aug 01, 2020
Accession Number
AD1115246

Entities

People

  • Jennifer Barton

Organizations

  • University of Arizona

Tags

Communities of Interest

  • Biomedical

DTIC Thesaurus Topics

  • Acquisition
  • Biomedical Engineering
  • Biomedical Research
  • Birds
  • Cancer
  • Contracts
  • Covid-19
  • Data Analysis
  • Detection
  • Detectors
  • Endoscopes
  • Engineering
  • Health
  • Health Services
  • Laser Diodes
  • Lasers
  • Light Sources
  • Medical Personnel
  • Neoplasms
  • Optical Properties
  • Optics
  • Ovarian Cancer
  • Standards
  • Students

Fields of Study

  • Medicine
  • Physics

Readers

  • Medical Imaging.
  • Software Engineering
  • Women's Health and Cancer Risk Research: African American Women and Pregnancy Outcomes.

Technology Areas

  • Directed Energy