Establishing Human and Animal Stool Testing for SARS-CoV-2 to Determine Feasibility of Fecal/Oral Transmission

Abstract

The Current COVID-19 disease pandemic is caused by the Coronavirus SARS-CoV-2. SARS-related viruses in humans are generally carried by animals and human infections are only due to contact with infected animals. But in the case of SARS-CoV-2, human to human transmission is the most studied route of infection and primarily through fomites or respiratory particulates. The objective of this project was to determine feasibility of methods to test and detect infectious SARS-CoV-2 virus and viral RNA in stool. Once detected, the results were used to support the hypothesis that fecal/oral exposure to SARS-CoV2 virus is a potential route of infection in animal models and humans and an area to address in the control and prevention of COVID-19 disease.

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Document Details

Document Type
Technical Report
Publication Date
Apr 16, 2021
Accession Number
AD1128507

Entities

People

  • Brittany Knight
  • Kenton L. Lohman
  • Lolly Gardiner
  • Sheldon Bradrick
  • Theresa Seitz
  • William Sosna

Tags

Communities of Interest

  • Human Systems

DTIC Thesaurus Topics

  • Biological Sciences
  • Contracts
  • Covid-19
  • Culture Techniques
  • Dilution
  • Disease Outbreaks
  • Diseases And Disorders
  • Homeland Defense
  • Infection
  • Infectious Diseases
  • Materials
  • Medical Personnel
  • New Hampshire
  • Optimization
  • Particulates
  • Recovery
  • Sars
  • Sensitivity
  • Standards
  • Test Equipment
  • Viruses
  • Wound Infections

Fields of Study

  • Biology

Readers

  • Infectious Disease/Epidemiology