Enhancing Operational Performance in Healthy Rested Soldiers with Pharmacological Stimulants

Abstract

Considerable research has documented the optimization utility of stimulants in sleep deprived Soldiers and aviators, however, the research for enhancement purposes has demonstrated mixed results. One significant factor that may influence enhancement properties is general intelligence such that low performers exhibit stronger enhancement effects than high performers. The objectives of this study were to: 1) determine whether stimulants (specifically, modafinil and mixed amphetamine salts) can enhance Soldier cognitive abilities and performance on military tasks while controlling for baseline intelligence, and 2) to document adverse or undesirable side effects of each stimulant. To do so, a within-subjects design was employed using healthy, rested Soldiers and measuring performance on a set of basic cognitive assessments and operationally relevant tasks. Results show that mixed amphetamine salts may be effective at enhancing functional performance in healthy, rested Soldiers, specifically marksmanship. The study results, overall, do not provide support for 200 mg of modafinil enhancing performance in healthy, rested Soldiers.

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Document Details

Document Type
Technical Report
Publication Date
Jun 10, 2021
Accession Number
AD1137965

Entities

People

  • Amanda M. Kelley
  • Claire Goldie
  • Colby Mathews
  • Ian Curry
  • Jared Basso
  • Jim Chiaramonte
  • John Crowley
  • Kyle Bernhardt
  • Melody King

Organizations

  • Oak Ridge Institute for Science and Education
  • United States Army

Tags

Communities of Interest

  • Biomedical
  • Human Systems
  • Weapons Technologies

DTIC Thesaurus Topics

  • Air Force
  • Cognition
  • Cognitive Workload
  • Data Displays
  • Diseases And Disorders
  • Human Behavior
  • Information Processing
  • Medical Personnel
  • Mental Disorders
  • Mental Processes
  • Performance Tests
  • Psychiatry
  • Psychology
  • Reaction Time
  • Reasoning
  • Side Effects
  • Statistical Analysis
  • Task Performance And Analysis
  • Technical Information Centers
  • United States

Readers

  • Circadian Sleep-Wake Regulation and Chronobiology
  • Psychological Intervention/Treatment for Stress, Anxiety, PTSD, and Related Emotional and Cognitive Health Symptoms.
  • Psychometric Testing or Psychological Assessment.