Minimally Invasive VAC Therapy with Instillation for Treating Infected Skin-Implant Interfaces in Percutaneous Osseointegrated Devices

Abstract

Percutaneous osseointegrated (OI) prosthetics are a superior alternative to socket-type prosthetics. Sadly, the weak link of this OI technology is high and re-occurring infection rates that originates from the implant post-exit sites. One potential method for treating infected tissue locally is the direct application of negative pressure wound therapy with installation (NPWTi) at the implant exit site. Thus, this proposal's overall goal is to successfully develop a NPWTi treatment plan for infected skin-implant interfaces of percutaneous OI devices. We have designed, developed, and fabricated all necessary implants and tools during this reporting period and obtained required institutional approvals. We also developed bacterial inoculation and animal surgical protocols.

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Document Details

Document Type
Technical Report
Publication Date
Aug 01, 2021
Accession Number
AD1152708

Entities

People

  • Jay Agarwal
  • Sujee Jeyapalina

Organizations

  • University of Utah

Tags

DTIC Thesaurus Topics

  • Animals
  • Anti-Bacterial Agents
  • Bacteria
  • Biomedical Research
  • Department Of Defense
  • Department Of Veterans Affairs
  • Engineering
  • Engineering Drawings
  • Infection
  • Medical Personnel
  • Prostheses And Implants
  • Prosthetics
  • Rodents
  • Students
  • Surgery
  • Therapy
  • Wound Infections

Readers

  • Systems Analysis and Design
  • Trauma Surgery or Emergency Medicine.