Synthesis of 2-Methoxypropyl Benzene for Epitope Imprinting
Abstract
Harmful algal blooms (HABs) are occurring with increasing frequency and severity across the globe in part due to climate change and anthropogenic pollution (Bullerjahn et al. 2016). HABs produce several classes of toxins; however, microcystins (MCs) are the most commonly studied (Lone et al. 2015) and can be potent toxins with LD50s in the range of 50 g/kg (Puddick et al. 2014). Sample analysis in laboratories, typically by high-pressure liquid chromatography tandem mass spectrometry (HPLC-MS/MS) or by Enzyme Linked Immunosorbent Assays (ELISAs) (USEPA 2015). These analytical techniques are highly sensitive and selective for the given toxins; however, the time it takes to collect, transfer, prepare, and analyze a sample before the data can be reported is significant; often, multiple days is the most expeditious.
Document Details
- Document Type
- Technical Report
- Publication Date
- Jul 27, 2022
- Accession Number
- AD1175201
Entities
People
- Garrett W. George
- I. Fernando
- Lee C. Moores
- P. U. Ashvin
Organizations
- Engineer Research and Development Center