Additional Studies Pertaining to the Mechanism of Cutaneous Injury by Mustard Gas. An Experimental Study Using Mustard Prepared with Radioactive Sulfur

Abstract

Investigations of the mechanism of mustard vesication were made primarily through parallel histological and chemical studies of skin exposed to mustard and related compounds prepared with radioactive sulfur. Details of the synthesis of benzyl mustard, sesqui-mustard, mustard sulfone, and divinyl sulfone are given. These tests were conducted to determine the following; the penetration rate of mustard through pig, rabbit, and human skin; the pathology of cutaneous injury following exposure to mustard; the significance and properties of fixed mustard in skin sites of man and pig; and a method of increasing the rate and severity of cutaneous injury by mustard. Additional investigations were made pertaining to the sulfonium salt, DH-TG.

Open PDF

Document Details

Document Type
Technical Report
Publication Date
Oct 25, 1945
Accession Number
AD1184216

Entities

People

  • A. R. Moritz
  • F. C. Jr Henriques
  • F. R. Dutra
  • L. A. Patterson

Organizations

  • Harvard University

Tags

DTIC Thesaurus Topics

  • Abdomen
  • Alcohols
  • Alkanes
  • Blood
  • Blood Plasma
  • Body Fluids
  • Cell Physiological Processes
  • Cells
  • Chemical Warfare
  • Connective Tissue
  • Epidermis
  • Epithelial Cells
  • Epithelium
  • Materials
  • Methanols
  • Sodium Compounds
  • Subcutaneous Tissue
  • Sulfur Compounds

Readers

  • Geochemistry
  • Organic Chemistry
  • Toxicology/Environmental Toxicology