Design of a 3D Mammography System in the Age of Personalized Medicine

Abstract

Digital breast tomosynthesis (DBT) is the latest 3D advancement in breast cancer screening. In conventional systems, the x-ray tube scans in one direction (left-to-right). We modeled a next-generation DBT system with an additional scanning motion in the posteroanterior (PA) direction. Defrise phantoms and anthropomorphic breast models were simulated. In the next generation design, there was higher area under the receiver-operating-characteristic curve (AUC) in the task of segmenting dense from adipose tissue. Also, in Defrise phantoms, AUC was optimized by personalizing the range of PA motion around the size of the phantom.

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Document Details

Document Type
Technical Report
Publication Date
Jul 01, 2022
Accession Number
AD1197539

Entities

People

  • Raymond J Acciavatti

Organizations

  • University of Pennsylvania

Tags

DTIC Thesaurus Topics

  • Artificial Intelligence
  • Breast Cancer
  • Computational Science
  • Computer Vision
  • Data Mining
  • Data Science
  • Databases
  • Detectors
  • Diagnostic Imaging
  • Dimensionality Reduction
  • Electronic Mail
  • Health Services
  • Image Processing
  • Information Science
  • Medical Personnel
  • Network Science
  • X-Ray Computed Tomography

Fields of Study

  • Medicine
  • Physics

Readers

  • Oncology and Biomarker-Based Cancer Detection.