A Method of Measuring Thyroid Burden of I125.

Abstract

Laboratory workers producing I125 labeled compounds may ingest or inhale small quantities of radioactive iodine which is deposited preferentially in the thyroid. Measurement of the thyroid burden is required to quantify the radiation dose to the individual and to provide early warning of possible health hazards. A rapid, accurate method of measuring thyroid burden using an Anger camera and pulse height analysis techniques was developed. The procedure requires 2 to 3 minutes, equipment commonly available in a nuclear medicine department, and causes no discomfort for the subject. The minimum detectable amount of I125 has been found to be approx. 1.0 nCi with a counting time of 100 seconds. The linearity of the method has been measured using on ORINS thyroid phantom and sources traceable to the NBS. The method is in regular use at the AFRRI and some results obtained from this use are presented. (Author)

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Document Details

Document Type
Technical Report
Publication Date
Jun 01, 1976
Accession Number
ADA033411

Entities

People

  • R. L. Donovan
  • W. R. Webber

Organizations

  • Armed Forces Radiobiology Research Institute

Tags

Communities of Interest

  • Biomedical
  • Energy and Power Technologies

DTIC Thesaurus Topics

  • Accuracy
  • Calibration
  • Collimators
  • Data Science
  • Detectors
  • Information Science
  • Linear Regression Analysis
  • Materials
  • Measurement
  • Nuclear Medicine
  • Radiation
  • Radiobiology
  • Regression Analysis
  • Spectra
  • Standards
  • X Rays

Fields of Study

  • Medicine
  • Physics

Readers

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  • Nuclear and Radiation Engineering.
  • Oncology and Biomarker-Based Cancer Detection.