Preparation of a Homologous (Human) Intravenous Botulinal Immune Globulin.

Abstract

An intravenous, botulinal, immune (human) globulin has been prepared from human immune plasma supplied by the United States Army Medical Research Institute of Infectious Diseases (USAMRIID) at Fort Detrick, Frederick, Maryland, and contains neutralizing activity to five botulinal neurotoxins: A, B, C, D and E. This final report contains details of all source materials, methods, procedures, testing and status of four lots of human, intravenous, hyperimmune, pentavalent, botulinal IgG that have been prepared and shipped to USAMRIID. These include lots IVBG-1A-553 grams, IVBG-1B--579 grams, IVBG-2A--563 grams, and IVBG-2B-401 grams for a total of 2096 grams. The information included in this report contains all the documentation required of products prepared for Investigational New Drug (IND) status.

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Document Details

Document Type
Technical Report
Publication Date
May 01, 1983
Accession Number
ADA141471

Entities

People

  • R. M. Condie

Organizations

  • University of Minnesota

Tags

Communities of Interest

  • Biomedical

DTIC Thesaurus Topics

  • Biological Factors
  • Biological Products
  • Biomedical And Dental Materials
  • Blood Coagulation
  • Blood Coagulation Factors
  • Blood Proteins
  • Chemical Synthesis
  • Chemistry
  • Health Services
  • Medical Personnel
  • Polymer Chemistry
  • Polymeric Films
  • Vaccines

Fields of Study

  • Medicine

Readers

  • Clinical Trial Research.
  • Immunology
  • Microbial Pathology