Dependence of the Log K Values for the Interaction of Chiral Dimethylpyridino-18-Crown-6 with Alpha-(1-Naphthylethyl) Ammonium Perchlorate on Several Solvent Parameters
Abstract
The log K values for the complexation of chiral dimentylpyridino-18-crown-6 with the (R)- and (S)- enantimoers of alpha-(1-naphthylethyl)ammonium percholrate were determined by the direct (1)H NMR technique(1) in a variety of solvents. The crown and salt are shown in Figure 1 along with the log K values. It is clear from the data in Figure 1 that the magnitude of log K correlates well with the solvent donor number (DN) but there is no correlation between log K values and the dielectric constant (epsilon/tau), acceptor number (AN) or empirical polarity (E/TAU(N)) of each solvent. Solvents with low donor numbers allowed the most stable complexation as would be expected. Solvents with high donor numbers would form strong solvent associations with the guest so that guest molecules would be less available for the chiral ligand. DMSI-d(s) associates so strongly with the ammonium salt that no complexation with the ligand was observed.
Document Details
- Document Type
- Technical Report
- Publication Date
- May 20, 1991
- Accession Number
- ADA236088
Entities
People
- C. Y. Zhu
- J. S. Bradshaw
- Reed Izatt
Organizations
- Brigham Young University