Prediction of Pathologic Fracture Risk in Activities of Daily Living and Rehabilitation of Patients with Metastatic Breast Carcinoma of the Pelvis and Femur

Abstract

The purpose of the project is to develop a computer model of the pelvis and proximal femur which can be used to predict pathologic fracture risk and study the effects of pelvic and proximal femoral metastatic bone lesions on the care and management of breast cancer patients. The scope of the research is to construct graphical and quantitative models of the pelvis and proximal femur on a computer workstations including Finite Element Method (FEM) and Discrete Element Method (DEM) to study the stress and strain in the pelvis and proximal femur and pressure distribution of the hip joint in the patient with metastatic bone lesions of the breast cancer in the pelvis and proximal femur with interactive capability. A simple FEM model with a bone defect was analyzed and the results were validated by mechanical testing. The DEM model was used to estimate the pressure distribution of the hip joint during Activity in Daily Living (ADL), including walking, climbing stairs, and getting up from a chair.

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Document Details

Document Type
Technical Report
Publication Date
Aug 01, 2001
Accession Number
ADA398168

Entities

People

  • Nozomu Inoue

Organizations

  • Johns Hopkins University

Tags

Communities of Interest

  • Biomedical

DTIC Thesaurus Topics

  • Bioengineering
  • Biomedical Research
  • Bone And Bones
  • Breast Cancer
  • Climbing
  • Computers
  • Coordinate Systems
  • Joint Diseases
  • Joints (Anatomy)
  • Mechanical Engineering
  • Medical Personnel
  • Musculoskeletal System
  • Neoplasms
  • Pelvis
  • Pressure Distribution
  • Rehabilitation
  • Simulations

Readers

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