In Vivo Validation of a One-Dimensional Finite Element Method for Simulation-Based Medical Planning for Cardiovascular Bypass Surgery

Abstract

Current practice in vascular surgery utilizes only diagnostic and empirical data to plan treatments, and does not enable quantitative a priori prediction of the outcomes of interventions. We have previously described simulation-based medical planning methods to model blood flow in arteries and plan medical treatments based oil physiologic modelsL, 2. These methods utilize computationally intensive three dimensional finite element analysis. We recently described a new method for simulation-based medical planning based oil solving one-dimensional equations of blood flow 3. We demonstrate herein that these one-dimensional methods can be used to stimulate blood flow in a porcine thoraco-thoraco bypass and further that predicted flow rates compare favorably to in vivo data obtained using cine phase-contrast magnetic resonance imaging in four pigs.

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Document Details

Document Type
Technical Report
Publication Date
Oct 25, 2001
Accession Number
ADA412230

Entities

People

  • B. N. Steele
  • C. A. Taylor
  • J. P. Ku
  • Jessica Wan
  • T. J. Hughes

Organizations

  • Stanford University

Tags

Communities of Interest

  • Biomedical

DTIC Thesaurus Topics

  • Arteries
  • Blood
  • Blood Flow
  • Boundaries
  • Cardiovascular Physiological Phenomena
  • Constitutive Equations
  • Differential Equations
  • Engineering
  • Equations
  • Finite Element Analysis
  • Flow
  • Flow Rate
  • Geometry
  • Magnetic Resonance
  • Partial Differential Equations
  • Surgery
  • Three Dimensional

Fields of Study

  • Medicine

Readers

  • Computational Fluid Dynamics (CFD)
  • Medical Imaging.
  • Trauma or Military Medicine