Multiple Aperture Radiation Therapy (MART) for Breast Cancer

Abstract

Conventional breast radiotherapy utilizes two opposed tangential fields (OTF) can result in high radiation dose to lung and heart and inhomogeneous dose distribution in the target for large-size breast. Modern advances in radiation therapy such as the intensity-modulated radiotherapy (IMRT) may be used to achieve dose distribution with superior tumor conformality and normal tissue spare. However, the increased complexity of the treatment planning and delivery procedures is a problem in a busy clinical environment. In this USAMRMC-supported project, we have developed a multiple-aperture radiation therapy (MART) procedure dedicated to breast irradiation, which combines the planning simplicity of the conventional OFT with the superior dose distribution of IMRT methods. The MART has been implemented in a clinic environment and systematically assessed. The improvement of dose distribution over traditional OTF has been clearly demonstrated. Furthermore, techniques related to breathing motion control have also been extensively investigated and included in this report.

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Document Details

Document Type
Technical Report
Publication Date
Nov 01, 2006
Accession Number
ADA466522

Entities

People

  • Tianfang Li

Organizations

  • Stanford University

Tags

Communities of Interest

  • Air Platforms
  • Energy and Power Technologies

DTIC Thesaurus Topics

  • Computational Science
  • Detectors
  • Diagnostic Imaging
  • Electronic Mail
  • Health Services
  • Medical Personnel
  • Radiation Oncology
  • Radiography
  • Radiotherapy
  • X-Ray Computed Tomography

Fields of Study

  • Medicine
  • Physics

Readers

  • Medical Imaging.
  • Nuclear and Radiation Engineering.
  • Systems Analysis and Design