Profiling Jet Fuel on Neurotoxic Components With Comprehensive Two-Dimensional GC
Abstract
Exposure to jet-propulsion fuel 8 (JP-8) is probably the most occurring chemical exposure within the military. The discussion on the possible adverse health effects of such an exposure is ongoing. Methodology is needed to identify and quantify low concentrations of potentially toxic components in the complex JP-8 matrix. Comprehensive GC (GCxGC), in which continuous two-dimensional separation occurs, was shown to be highly suitable for this purpose. =In combination with time-of-flight mass-spectrometry up to 3,500 components in JP-8 could be chromatographically resolved, in most cases identified and (semi-)quantified. Differences in composition between JP-8 from various sources and with various ages were demonstrated. This technology was used to establish the evaporation profiles at -10 and 20 C of 20 components that are considered to be potentially neurotoxic. Rough estimates of the external exposures of personnel were made from these evaporation profiles as well as preliminary toxicological evaluations.
Document Details
- Document Type
- Technical Report
- Publication Date
- Nov 01, 2007
- Accession Number
- ADA475160
Entities
People
- Henk C. Trap