Three-Dimensional Near Infrared Imaging of Pathophysiological Changes Within the Breast
Abstract
Near Infrared optical imaging is a non-invasive and non-ionizing medical imaging technique that can image functional properties of biological tissue using Near Infrared (NIR) light. Due to the dominance of scattering of light in tissue, modeling of light propagation in tissue requires advanced computational methods. This project was aimed to develop novel computational methods that will lead to use of optical imaging in a routine clinical setting. As a part of this work, an optimization of computational parameters for the existing methods was performed. A novel algorithm which includes noise characteristics of the instruments was also developed to get an optimal estimate of breast tissue optical properties. New methods for effectively using Magnetic resonance image information in NIR image reconstruction procedure were also developed to improve the total outcome of NIR functional images of breast. Optical image reconstruction methods that improve the computational efficiency by a factor of 10 for three-dimensional optical imaging were also developed.
Document Details
- Document Type
- Technical Report
- Publication Date
- Mar 01, 2008
- Accession Number
- ADA481191
Entities
People
- Phaneendra K. Yalavarthy
Organizations
- Dartmouth College