Nanotechnology-Enabled Optical Molecular Imaging of Breast Cancer
Abstract
This project focuses on development of nanotechnology-enabled optical molecular imaging technologies for applications in breast cancer diagnosis and monitoring of therapeutic response. The project consists of two major efforts: (1) optical instrumentation technology development and (2) development of complementary engineered nanomaterials for use in conjunction with the instrumentation created to provide molecular specificity. A particularly significant effort is underway to develop needle-compatible fiber optic probes to enable in vivo imaging of tumors with micron resolution in order to provide a new microscopic, high resolution imaging modality to complement the low resolution, macroscopic imaging modalities already in common clinical use. Nanoengineered materials including shaped and layered gold nanoparticles and cadmium-free luminescent dots targeted to molecular signatures of breast cancer are being developed with properties optimized for the specific optical imaging strategies created.
Document Details
- Document Type
- Technical Report
- Publication Date
- Jul 01, 2008
- Accession Number
- ADA502699
Entities
People
- Rebekah Drezek
Organizations
- Rice University