Development and Optimization of a Dedicated, Hybrid Dual-Modality SPECT-CmT System for Improved Breast Lesion Diagnosis

Abstract

The overall objective of this project is to implement a dual-modality single photon emission computed tomography (SPECT) and x-ray computed mammotomography (CmT) system for the detection and staging of breast cancer, monitoring of treatment therapies, and improving surgical biopsy guidance. The sequential acquisition with emission (nuclear) and transmission (x-ray) 3D imaging systems can aid in localizing the radioactive uptake of a tumor from the emission image by using the anatomical structure from the transmission image. In the second year, CmT artifacts due to the lateral offset geometry and scatter were investigated. Using the data acquisition sequence developed in Year 1, a couple of patient studies were also completed to demonstrate the strength in 3D volumetric dual-modality imaging with the dedicated SPECT-CmT breast scanner. Other aspects of the training program have been initiated including acceptance of one manuscript to a peer-reviewed journal and presentations at various local and international conferences.

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Document Details

Document Type
Technical Report
Publication Date
Jan 01, 2009
Accession Number
ADA502836

Entities

People

  • Priti Madhav

Organizations

  • Duke University

Tags

Communities of Interest

  • Biomedical

DTIC Thesaurus Topics

  • Acquisition
  • Breast Cancer
  • Data Acquisition
  • Detection
  • Detectors
  • Diagnostic Imaging
  • Geometry
  • Health Services
  • Imaging Techniques
  • Medical Personnel
  • Neoplasms
  • Prostheses And Implants
  • Prosthetics
  • Radiation
  • Tomography
  • X Rays
  • X-Ray Computed Tomography

Fields of Study

  • Medicine
  • Physics

Readers

  • Medical Imaging.