Integration of Diagnostic and Interventional MRI for the Study of Persistent Prostate Cancer After External Beam Radiotherapy
Abstract
This study involves the technical development and clinical testing of a novel technique for magnetic resonance imaging (MRI) guided prostate biopsy in a 1.5T horizontal bore scanner using a dedicated interventional table. We primarily hypothesize that the integration of diagnostic and interventional MRI enables needle biopsy targeting to foci of tumor recurrence after radiotherapy, and will enable a determination of the diagnostic accuracy of MRI in mapping sub-sites of tumor recurrence after radiotherapy. From September 2007 to September 2008, accrual to stages 1 and 2 of the trial was completed. One patient was also accrued to stage 3 of the trial. Here we report tasks 1e and 2a of Aims1 and 2. Clinical needle targeting accuracy has been maintained at 2mm, and motion improved. A method for 3D mapping of tumor using FEM analysis has be developed and reported here.
Document Details
- Document Type
- Technical Report
- Publication Date
- Oct 01, 2008
- Accession Number
- ADA506484
Entities
People
- Cynthia Ménard
Organizations
- University Health Network