Non-Invasive Nanodiagnostics of Cancer (NINOC)

Abstract

This project seeks to develop noninvasive diagnostics to detect cancer in its earliest, most easily treatable, pre-symptomatic stage. Innovative imaging nanomaterials and delivery technologies are employed to target, label, and detect the cancer cells within the body at sites which are normally inaccessible to conventional diagnostic methods. The hydrophilic polymer nanogels of core-shell emission computed tomography, computer tomography, magnetic resonance, or luminescence detection. The surface of the nanogels is modified with genetically engineered antibody fragments to target the surface of cancer cells and provide site-specific delivery of the nanogels to tumors in the body.

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Document Details

Document Type
Technical Report
Publication Date
Jun 01, 2009
Accession Number
ADA511285

Entities

People

  • Alexander Kabanov

Organizations

  • University of Nebraska Medical Center

Tags

Communities of Interest

  • Biomedical

DTIC Thesaurus Topics

  • Albumins
  • Alkenes
  • Antibodies
  • Biomedical And Dental Materials
  • Biomedical Research
  • Block Copolymers
  • Colon Cancer
  • Detectors
  • Flow Rate
  • Materials
  • Particles
  • Polymeric Films
  • Polymers
  • Proteins
  • Resonance
  • Surface Plasmon Resonance
  • Surface Plasmons

Fields of Study

  • Physics

Readers

  • Fault Tolerant Diagnosis of Black and White Balloon Isolation Tests Using ¥.
  • Medical Imaging.
  • Molecular and Cellular Biochemistry

Technology Areas

  • Biotechnology
  • Biotechnology - Cancer Biotech