UCLA High Speed, High Volume Laboratory Network for Infectious Diseases. Addendum

Abstract

Objectives/Hypothesis: This project aims to develop a new kind of high-throughput laboratory and informatic capability. It will provide a platform (high-speed high-volume processing, accessioning, archiving, screening, genotyping, culturing, phenotyping) for data-driven science and discovery. This platform is first being developed for influenza and can be expanded to include other pathogens as well. Integrated bioinformatics will associate surveillance information from the field with laboratory data and enable data-driven science and discovery against emerging and engineered biothreats. Specific Aims: With FY06 (Initial Year), FY07 (OY1) and FY08 (OY2) Congressional appropriations, high-throughput bioagent Automated Genotyping System has been implemented first and are currently in the process of purchasing an initial unit of the Automated Archiving System. In addition, 100% specifications for both the Automated Culturing System and Automated Screening System have been produced; RFPs have been released by UCLA Purchasing in February 2010. The Automated Screening System will be purchased with OY2 funds. With FY09 (OY3) Congressional appropriations, the Automated Culturing System will be purchased. In addition, OY3 funds will be used to complete specifications for the Automated Phenotyping System. If FY10 (OY4) Congressional appropriations are approved (or if other funds become available), these funds will be used to purchase the Automated Phenotyping System and two additional units of the Automated Archiving System. The automated systems will be housed in laboratory space at UCLA that has been upgraded to BSL3-enhanced (BSL3e) containment (to be completed in OY2) that enables the flow of numerous samples containing Highly Pathologic Avian Influenza and other Select Agents (dual-use).

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Document Details

Document Type
Technical Report
Publication Date
Aug 01, 2009
Accession Number
ADA518266

Entities

People

  • Hilary Godwin
  • Jeffrey F. Miller
  • Scott P. Layne

Organizations

  • University of California, Los Angeles

Tags

Communities of Interest

  • Biomedical

DTIC Thesaurus Topics

  • California
  • Chemical Synthesis
  • Chemistry
  • Control Systems
  • Data Science
  • Department Of Defense
  • Diseases And Disorders
  • Homeland Security
  • Infectious Diseases
  • Information Systems
  • Medical Personnel
  • National Security
  • Public Health
  • Respiratory Tract Diseases
  • Security
  • United States
  • Viruses

Readers

  • Database Systems and Applications
  • Fault Tolerant Diagnosis of Black and White Balloon Isolation Tests Using ¥.
  • Molecular and genetic basis of cancer.

Technology Areas

  • Space