High Resolution PET Imaging Probe for the Detection, Molecular Characterization and Treatment Monitoring of Prostate Cancer
Abstract
The goal of this work is to improve methods of molecular imaging for diagnosis as well as treatment planning and monitoring in prostate cancer. This investigation hypothesizes that a dedicated endorectal probe for positron emission tomography (PET) will provide significant improvements in image quality over conventional, external-ring PET scanners used alone. The project is developing prototype high resolution PET detectors that have the possibility of endorectal use and is evaluating potential advantages using phantom studies prior to use in human subjects. Progress to date has been significant with the development of several prototype detectors that achieve desired resolution performance and that will be interfaced to a partial-ring PET system for testing in the upcoming year. Particularly exciting from the viewpoint of developing devices that can be tested clinically was interest in the technology by a major manufacturer of conventional PET instruments.
Document Details
- Document Type
- Technical Report
- Publication Date
- Jul 01, 2010
- Accession Number
- ADA534960
Entities
People
- Neal H. Clinthorne
- Stan Majewski
Organizations
- United States Army Medical Research and Development Command