Photonic Breast Tomography and Tumor Aggressiveness Assessment
Abstract
The tasks performed and the progresses made during the third year include: (a) participation in magnetic resonance (MR) imaging and spectroscopy experiments for lactate detection following training at the Memorial Sloan Kettering Cancer Center (MSKCC); and (b) conducting research on development of non-invasive optical imaging and spectroscopic approaches for breast tumor detection. The CCNY researchers constructed specialized coils for sensitive MR investigation, developed lactate phantoms, and investigated the feasibility of lactate concentration measurement at the MSKCC MR facility. Accurate in vivo measurement of lactate concentration in an animal model is expected to help assess if a tumor is fast growing, or slow growing. The near-infrared optical imaging research involved development of time reversal optical tomography (TROT) approach for imaging of absorbing target(s), OPTICA (optical tomography using independent component analysis) investigation for locating tumors in a realistic model cancerous breast assembled using ex vivo breast tissues. OPTICA could locate both the tumors, and the results agreed well with the results of MRI investigation of the same model breast. A new research proposal was developed and submitted to CDMRP 2010 BCRP Idea Award category for funding.
Document Details
- Document Type
- Technical Report
- Publication Date
- Jul 01, 2010
- Accession Number
- ADA540734
Entities
People
- S. K. Gayen
Organizations
- New York University