Isolation and Characterization of Trioxyethylene-Encapsulated Gold Nanoclusters Functionalized with a Single DNA Strand

Abstract

A scalable means of isolating significant quantities of trioxyethylene-encapsulated gold nanoclusters (GNCs) labeled with a single DNA strand is demonstrated. Quantitative characterization of the product is obtained using UV-vis absorbance spectroscopy. These methods of isolation and characterization of singly functionalized GNC-ssDNA conjugates are expected to aid development of nanoscience applications that use DNA molecular recognition for guiding self-assembly.

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Document Details

Document Type
Technical Report
Publication Date
Mar 02, 2004
Accession Number
ADA575320

Entities

People

  • Arthur W. Snow
  • Daniel A. Lowy
  • Eddie L. Chang
  • Edward E. Foos
  • Mario G. Ancona
  • Sulay D. Jhaveri

Organizations

  • United States Naval Research Laboratory

Tags

Communities of Interest

  • Materials and Manufacturing Processes

DTIC Thesaurus Topics

  • Abstracts
  • Charge Density
  • Dielectric Permittivity
  • Electrophoresis
  • Exchange Reactions
  • Extraction
  • Fabrication
  • Fluorescence
  • Gel Electrophoresis
  • Identification
  • Manufacturing
  • Military Research
  • Nanoparticles
  • Recognition
  • Self Assembly
  • Spectra
  • Spectroscopy

Fields of Study

  • Chemistry

Readers

  • Molecular and Cellular Biochemistry
  • Nanoscale Plasmonic Nanotechnology