High Resolution PET Imaging Probe for the Detection, Molecular Characterization, and Treatment Monitoring of Prostate cancer

Abstract

The goal of this work is to improve methods of molecular imaging for diagnosis as well as treatment planning and monitoring in prostate cancer. This investigation hypothesizes that a dedicated endorectal probe for positron emission tomography (PET) will provide significant improvements in image quality over conventional, external-ring PET scanners used alone. The project is developing prototype high resolution PET detectors that have the possibility of endorectal use and is evaluating potential advantages using phantom studies prior to use in human subjects. Progress to date has been significant with the development of several prototype detectors that achieve desired resolution performance and that will be interfaced to a partialring PET system for testing in the upcoming year. Particularly exciting from the viewpoint of developing devices that can be tested clinically was interest in the technology by a major manufacturer of conventional PET instruments.

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Document Details

Document Type
Technical Report
Publication Date
Jul 01, 2011
Accession Number
ADA602058

Entities

People

  • Neal H. Clinthorne
  • Stan Majewski

Organizations

  • West Virginia University

Tags

Communities of Interest

  • Advanced Electronics
  • Biomedical
  • Energy and Power Technologies

DTIC Thesaurus Topics

  • Application-Specific Integrated Circuits
  • Detection
  • Detectors
  • Electronics
  • Emission
  • High Resolution
  • Monitoring
  • Neoplasms
  • Positron Emission Tomography
  • Positron Emissions
  • Positrons
  • Prostate
  • Prostate Cancer
  • Prototypes
  • Scattering
  • Three Dimensional
  • Tomography

Fields of Study

  • Physics

Readers

  • Medical Imaging.