Technologies for Hemostasis and Stabilization of the Acute Traumatic Wound

Abstract

The purpose of this research is to advance hemostasis technology, and to develop effective hemostatic devices for two difficult types of hemorrhage: (1) traumatic noncompressible (also known as truncal) hemorrhage; and (2) traumatic hemorrhage in the cold coagulopathic subject. The scope of this research will include both military and civilian trauma victims, particularly those suffering from hemorrhagic truncal injury and/or coagulopathic hemorrhage, from both penetrating and blunt mechanism. During the second (Y2) year of this project, we continued to generate stocks of two vitally important clotting factors (fibrinogen and Factor XIII), which we need for the development and manufacture of our hemostatic devices. In addition, we further developed prototypical methods to deliver foaming technology for the treatment of noncompressible hemorrhage. We also generated a reliable model for noncompressible torso hemorrhage. Importantly, we have continued to develop our single and dual foam technologies to treat noncompressible hemorrhage. In Y3 we will continue to perform extensive testing of these technologies.

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Document Details

Document Type
Technical Report
Publication Date
Oct 01, 2013
Accession Number
ADA602120

Entities

People

  • Gustavo Larsen
  • Luis Nunez
  • Mark A. Carlson
  • William H. Velander
  • Wilson H. Burgess

Organizations

  • University of Nebraska Omaha

Tags

Communities of Interest

  • Biomedical

DTIC Thesaurus Topics

  • Blood
  • Blood Coagulation Factors
  • Cardiovascular Physiological Phenomena
  • Chemical Synthesis
  • Chemistry
  • Health Services
  • Medical Personnel
  • Veins

Fields of Study

  • Medicine

Readers

  • Trauma Surgery or Emergency Medicine.