Cesium-137 Decorporation Model

Abstract

A treatment model for Cs-137 internal contamination by Prussian Blue was developed to evaluate efficacy of various treatment regimens. The model estimates Cs deposition, absorption, distribution, retention, excretion, and response to DTPA after an inhalation exposure. It estimates the acute red bone marrow and whole body effective dose as a function of time. Model results compare favorably with human and animal data. Outputs from the model include Cs deposition in the respiratory tract, distribution in tissue compartments over time with and without treatment, excretion rates, and radiation doses to critical organs. Calculations from the model may be used to analyze consequences of exposure to Cs and the effect of treatment.

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Document Details

Document Type
Technical Report
Publication Date
Oct 01, 2014
Accession Number
ADA613961

Entities

People

  • Daniela Stricklin
  • Gene E. Mcclellan
  • Jason Rodriguez
  • Kyle K. Millage

Organizations

  • Applied Research Associates (United States)

Tags

DTIC Thesaurus Topics

  • Blood Volume
  • Bodily Secretions
  • Bone Marrow
  • Bones
  • Contracts
  • Cyanides
  • Department Of Defense
  • Dose Rate
  • Dwell Time
  • Gastrointestinal Tract
  • Health Services
  • Medical Countermeasures
  • Particle Size
  • Radiation
  • Radioactive Decay
  • Skeleton
  • Small Intestine

Readers

  • Electronics Engineering
  • Statistical inference.
  • Toxicology/Environmental Toxicology