An Implantable Neuroprosthetic Device to Normalize Bladder Function after SCI

Abstract

The long-term goal of our project is to develop a novel neuroprosthetic device to restore the functions of the urinary bladder for SCI people without further damaging the nervous system. Advanced technologies in electrical and computer engineering will be applied to design the novel neuroprosthetic device. Based on our previous studies, we propose in this project to use pudendal nerve stimulation and blockade to restore both continence and micturition after SCI. Our strategy does not require sacral posterior root rhizotomy, preserves the spinal reflex functions of the bowel and sexual organs, and more importantly provides the opportunity for SCI people to benefit from any advance in neural regeneration and repair techniques in the future. During the last 3 years, we have successfully designed and developed a wireless controlled, wireless charged, small implantable stimulator for pudendal nerve stimulation and/or block, and tested its functionality in animal experiments using cats. These results have laid the foundation for us to further design and develop an implantable stimulator for human application in the future.

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Document Details

Document Type
Technical Report
Publication Date
Dec 01, 2014
Accession Number
ADA624765

Entities

People

  • Changfeng Tai

Organizations

  • University of Pittsburgh

Tags

DTIC Thesaurus Topics

  • Anesthesia
  • Biomedical Engineering
  • Catheterization
  • Computer Programs
  • Computers
  • Engineering
  • Health Services
  • Membrane Potentials
  • Military Medicine
  • Nerve Blocking
  • Nervous System
  • Neurosciences
  • Pain
  • Peripheral Nervous System
  • Urinary Tract
  • Urinary Tract Physiological Phenomena
  • Waveforms

Fields of Study

  • Medicine

Readers

  • Neuroscience
  • Neurotrauma and Rehabilitation Medicine.
  • Systems Analysis and Design