Developing Novel Conjugate HIV-1 Subunit Therapeutic Vaccines.

Abstract

Over the past several years, conjugate vaccines have met with much greater success and a number of these vaccines have received United States Food and Drug Administration (FDA) approval for use in adults and infants. Thus, it is the overall objective of this research project to assess the potential of an HIV-1 envelope glycoprotein (gp120) conjugate-based vaccine to induce high, long-lasting anti-HIV-1 envelope antibody titers with group specific neutralizing activity against primary and laboratory isolates of HIV-1.

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Document Details

Document Type
Technical Report
Publication Date
Jun 01, 1996
Accession Number
ADB218771

Entities

People

  • Tran C. Chanh

Organizations

  • Texas Biomedical Research Institute

Tags

DTIC Thesaurus Topics

  • Biomedical And Dental Materials
  • Biomedical Research
  • Cells
  • Chemical Synthesis
  • Chemistry
  • Immune Serums
  • Immunogenicity
  • Laboratory Animals
  • Lymphocytes
  • Molecular Dynamics
  • Organic Chemistry
  • Polymer Chemistry
  • Polymeric Films
  • Rodents
  • Vaccines

Fields of Study

  • Biology

Readers

  • Clinical Trial Research.
  • Immunology

Technology Areas

  • Biotechnology